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Caveolin-1 rabbit pAb

簡要描述：SourceRabbitApplicationsWB

  • 產(chǎn)品型號：
  • 廠商性質(zhì)：生產(chǎn)廠家
  • 更新時間：2025-01-12
  • 訪  問  量：116

詳細(xì)介紹

  • Source

    Rabbit

  • Applications

    WB,IHC,IF,ELISA

  • Reactivity

    Human,Mouse,Rat

  • Dilution

    WB 1:500-2000, IF 1:50-300, IHC 1:50-300

  • Storage

    -20°C/1 year

  • Specificity

    Caveolin-1 Polyclonal Antibody detects endogenous levels of Caveolin-1 protein.

  • Source/Purification

    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

  • Immunogen

    The antiserum was produced against synthesized peptide derived from human Caveolin-1. AA range:129-178

  • Uniprot No

    Q03135

  • Alternative names

    CAV1; CAV; Caveolin-1

  • Form

    Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

  • Clonality

    Polyclonal

  • Isotype

    IgG

  • Background

    caveolin 1(CAV1) Homo sapiens The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq, Mar 2010],

  • Other

    CAV1, Caveolin-1

  • Mol.Wt (Da)

    20472

  • Concentration

    1 mg/ml

Product Reactivity Applications Conjugation Catalog Images

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